Xu et. al. 2013

“Silver show effective treatment for fungal keratitis, which is emerging as a major cause of vision loss”

Chaw et. al. 2005

“The study on the intermolecular forces within the EPSs of S. epidermidis RP62A and S. epidermidis 1457 biofilms suggest
that the silver ions can destabilize the biofilm matrix by binding to electron donor groups of the biological molecules.
This leads to reductions in the number of binding sites for hydrogen bonds and electrostatic and hydrophobic interactions
and, hence, the destabilization of the biofilm structure.”

Nam et. al. 2015

“In various different forms, silver is capable of aiding the wound healing process, mainly through its antibacterial activity.
The broad spectrum of the silver ion’s antibacterial activity—a result of the multiplicity of the bactericidal mechanism
has proven itself to be effective on a variety of bacteria species in multitudinous studies.”

Noorbakhsh et. al. 2011

“Results demonstrated that silver can inhibited the fungus more efficiency than flocunazole.
The antifungal activity of flocunazole and geriseofulvin were increased in combination with silver.”

Lee et. al. 2010

“This result show that silver at 3 PPM could be applied as therapeutic agents regarding human fungal diseases with low
cytotoxicity as the result indicates that silver affected fungus cells by attacking their membranes, thus disrupting membrane
potential and inhibited some fungal RNA processes which are involved in fungal bud growth. The fact that silver is cost-effective
is also of importance as it can be expected that silver has potential as an anti-infective agent for human fungal diseases.”

Lkhagvajva et. al. 2011

“The results have demonstrated that water bound silver dispersions show a pronounced antibacterial effect,
as evidenced by a very low concentration of 2–4 PPM of silver particles against all tested microorganisms.
This very high activity could be related to the advantages induced through the water bound method since very
small silver particles were obtained which makes them very active against microorganisms. SEM investigations
of the morphology changes of those bacteria showed that the surfaces of the cell walls of both bacteria were
disrupted by Ag nanoparticles.”

Mikihiro et. al. 2005

“The study shows that the expression of a ribosomal subunit protein, as well as that of some other enzymes
and proteins of the anaerobic prokaryote cell necessary for the metabolism of the microbe, is affected by
the silver ion and the harmful development of the organism is disrupted and the anaerobic prokaryote cell
is suffocated and discharged by the immune system.”

Kalimuthu et.al.2010

“Staphylococci epidermis biofilms have been found to be markedly impaired by very low, non-inhibitory levels of silver ions.
This is important news, since biofilms give communities of microorganisms a distinct ability to resist antibiotic drugs.
If low levels of silver ions can impair biofilms, then its use may well help resolve one factor in the growing problem of
antibiotic-resistant microorganisms. The studies on the intermolecular forces within the EPSs of S. epidermidis and
S. epidermidis biofilms suggest that the silver ions can destabilize the biofilm matrix by binding to electron donor groups
of the biological molecules. This leads to reductions in the number of binding sites for hydrogen bonds and electrostatic and
hydrophobic interactions and, hence, the destabilization of the biofilm structure. After the addition of silver ions and within
60 min of contact, the overall structure of the biofilm became partially destroyed and the inner structure of biofilm was exposed.
There were also significant amounts of silver around the damaged biofilm colony, confirming the effect of silver ions on grown biofilm.”

Kalishwaralal et. al. 2010

“The study consequently affirm the application of silver nanoparticles as a boon to ocular therapies.”

Tian et. al. 2007

“The study investigated the wound-healing properties of silver nanoparticles in an animal model and found
that rapid healing and improved cosmetic appearance occur in a dose-dependent manner. Furthermore, through
quantitative PCR, immunohistochemistry, and proteomic studies, we showed that silver nanoparticles exert
positive effects through their antimicrobial properties, reduction in wound inflammation, and modulation
of fibrogenic cytokines. These results show the actions of silver and have provided a novel therapeutic
direction for wound treatment in clinical practice.”

Kim et. al. 2008

“Spherical silver nanoparticles (nano-Ag) were synthesised and their antifungal effects on fungal pathogens of the
skin were investigated. Silver ions showed potent activity against clinical isolates of Trichophyton mentagrophytes
and Candida. The activity of Silver ions was comparable to that of amphotericin B, but superior to that of fluconazole
The results show that silver ions exert activity on the mycelia. The study indicates that Silver ions have considerable
antifungal activity.”

Monteiro et. al. 2011

“The Study show that 3 PPM silver is very acgtive against biofilm of fungai.”

Singh et. al. 2012

“The present report provides the first ever conclusive proof in support of apoptosis as a novel stratagem in
antifilarial drug designing and nanoscale silver as a valid lead in research on antifilarial therapeutics.
Effective microfilaricidal activity of nanosilver at relatively low concentrations as reported in this study,
with evidence of the induction of apoptosis in microfilariae, projects nanosilver as a potential drug adjuvant
against lymphatic filariasis. The much higher 50% lethal dose value of nanosilver compared to the complete
inhibitory concentration value reported in this study argues in favour of a safe therapeutic window of this
agent in its antifilarial efficacy.”

Park et. al. 2010

“An antioxidant effect of silver nanoparticles could be one of the molecular bases in the murine model of asthma.
These findings may provide a potential molecular mechanism of silver nanoparticles in preventing or treating asthma.”

Van Amber Brown 1915

“In this study we see, in vivo as in vitro, that this colloidal silver possesses the requirements demanded in a
chemical general antiseptic.”

Berger et. al. 1976

“The study demonstrated that anodic silver (Ag+) at 3 PPM concentration have inhibitory and fungicidal properties.
Broth dilution susceptibility tests were made on several species of Candida and one species of Torulopsis. Growth in all
isolates was inhibited by concentrations of electrically generated silver ions between 0.5 and 4.7 mg/ml, and silver
exhibited fungicidal properties at concentrations as low as 1.9 ,ug/ml. The inhibitory and fungicidal concentrations of
electrically generated silver ions are lower than those reported for other silver compounds.”

Iroha et. al. 2007

“Colloidal silver at 5 ppm concentration has proven to be effective on ten clinical bacterial isolates comprising
five isolates of Escherichia coli isolated from surgical wound patients at the Federal Medical Centre, Abakaliki
and five isolates of Staphylococcus aureus isolated from the wound sites of burnt patients at the University of
Nigeria Teaching Hospital. Also, interaction studies between colloidal silver and some conventional antibiotics
were carried out showing that the test organisms were sensitive to the colloidal silver at both alone and with
antibiotics and the silver showed no antagonism to the antibiotic drug.”

Li et. al. 2010

“After being exposed to silver, the bacteria membrane vesicles were dissolved and dispersed, and their membrane
components became disorganized and scattered from their original ordered. In conclusion, the combined results
suggested that silver ions may damage the structure of bacterial cell membrane and depress the activity of some
membranous enzymes, which cause E. coli bacteria to die eventually.”

Becker et. al. 2002

“Free silver ions put into human wounds besides their antibacterial effect in clinical use as an addition has proven to have dedifferentiation of mature cells into progentitor stems cells producing a regeneration of local tissue of the skin.”

Assar et. al 2010

“The study conclude and show a successful formation of Colloidal Silver through its antibacterial activity on
S. aureus, E. coli, P. aregnosa and S. typhi.

Iroha et. al 2008

“Colloidal silver concentrate have an antibacterial activity against pathogenic P. aeruginosa and the
killing rate kinetics studies reveal that the test organisms were completely killed within 90 min.
Further exploitation of colloidal silver for the treatment of multi-drug resistant P. aeruginosa
infections is hereby suggested.”

Humberto et. al 2009

“Silver nanoparticles are effective broad-spectrum biocides against a variety of drug-resistant bacteria,
which makes them a potential candidate for use in pharmaceutical products and medical devices that may help
to prevent the transmission of drug-resistant pathogens in different clinical environments.”

Jung et. al. 2008

“Transmission electron microscopy showed considerable changes in the bacterial cell membranes upon silver ion treatment,
which might be the cause or consequence of the bacterial death. In conclusion, the results of the present study suggest
that silver ions may cause S. aureus and E. coli bacteria to reach an ABNC state and eventually die.”

Becker et. al. 2000

“A significant stimulation in open wounds have been noticed using silver for infection prevention where
local tissue regeneration was noted due to dedifferentiation of mature cells or stimulation of stem cells
in the wound, resulting in the production of large numbers of progenitor cells.”

Feng et. al. 20000

“Silver is discovered to destroy pathogens by attaching to DNA and preventing the pathogen metabolism and replication.”

Wesley et. al. 2005

“Silver has been used for at least six millennia to prevent microbial infections and was the most important
antimicrobial agent available before the introduction of antibiotics. Silver also has played an important role
in the development of improving wound healing.”

Danish Environmental Protection Agency 2012

“Danish Ministry of the Environment, found that nanosilver in textiles including various forms of clothing as well as
cleaning cloths and children’s toys pose no risk of health effects or environmental effects.”

Maass et. al. 2008

“Silver nanoparticles do not remain “nanosize” when they come in contact with normal environmental samples,
such as soil and water,but they agglomerate to form much larger, much less biologically effective, silver
particles which are non-toxic, non-ionic and have no history of being harmful to the environment or aquatic life.”

Klippstein et. al. 2010

“Dermatitis was induced on the ears of BALB/c mice using dinitrofluorobenzene and of silver, applied once a day for four days.
The results showed significant reductions of ear swelling, erythema and histopathological inflammation with no significant
difference between treatments.

Altman et. al. 1999

“Ingestion of properly prepared Colloidal Silver does not result in silver accumulating in the body.”

MANEEWATTANAPINYO et. al. 2011

“Oral administration of AgNPs at a limited dose of 5,000 mg/kg produced neither mortality nor acute toxic signs.
The results indicated that the LD50 of colloidal AgNPs is greater than 5,000 mg/kg body weight.”
This safe concentration is yet about 100 times higher than SilverLife 3 PPM silver solution.